21c Museum Hotel Cincinnati by MGallery

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The 21c Museum Hotel Cincinnati is the perfect place to start an adventurous journey into The Queen City. The hotel is just a short distance from several iconic destinations, including the Great American Ballpark and the Smale Riverfront Park. The hotel’s proximity to Downtown offers travelers easy access to local cultural attractions. Cincinnati/Northern Kentucky Int’l Airport: 13.4 miles, 20 minutes.

Driving Directions

  • I-75 N to West 5th St in Cincinnati.
  • Take exit 1C from I-75 N
  • Follow West 5th St to Vine St turn left
  • Turn right on 7th St
  • Turn right on Walnut St
  • 21c Museum Hotel Cincinnati will be on the left #609

Nearest Airport

Cincinnati / Northern Kentucky International Airport (CVG): 13.1 miles/16-24 minutes away

Hotel Address

609 Walnut Street, Cincinnati

Ohio, United States 45202

Historic Hotels of America Recommended Points of Interest

  • American Sign Museum

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  • Cincinnati Art Museum

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  • Cincinnati Museum Center At Union Terminal

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  • Cincinnati Zoo & Botanical Garden

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  • Harding Home Presidential Site

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    Discover the residence of former U.S. President Warren G. Harding.

  • Krohn Conservatory

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    Spend time outside in Cincinnati at the famous Krohn Conservatory.

  • Mt. Airy Forest

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    Hike through the verdant Mt. Airy Forest.

  • National Underground Railroad Freedom Center

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    Experience the historical legacy of the Underground Railroad.

  • Newport Aquarium

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  • Rutherford B. Hayes Presidential Library & Museums

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    Experience the legacy of former U.S. President Rutherford B. Hayes.

  • William Howard Taft National Historic Site

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    Explore the home of former U.S. President William Howard Taft.

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