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1528 Locust Street St. Louis, Missouri 63103
The original property opened in 1926. A member of Historic Hotels of America since 2023.
Awards & Accolades
21c Museum Hotels has revived a 10-story, Renaissance Revival-style YMCA building in the historic heart of St. Louis, becoming its tenth 21c Museum Hotel. The hotel is located right in the heart of downtown St. Louis, and a short walk from the City Museum and CITYPARK stadium. 21c Museum Hotel St. Louis is a 173-room boutique hotel, as well as boasting a contemporary art museum, Idol Wolf restaurant, Good Press café, and a full-service wellness center. With more than 14,000 square feet of exhibition and event space seamlessly integrated into all areas of the property, there are opportunities for visitors to discover contemporary art around every corner.
21c Museum Hotel St. Louis has been named to these Historic Hotels of America Top 25 Lists
The 2024 Top 25 Historic Hotels of America Best of Adaptive Reuse List
Location Map
Visit the St. Louis Aquarium and see blue lobsters and stingrays.
Discover
Discover the former YMCA building that has been restored into an award-winning boutique hotel in Downtown St Louis.
Explore
Enjoy the day at City Museum, a fun and quirky museum fit for all ages and interests.
Experience
Experience St. Louis most iconic landmark, the Gateway Arch, a 630-foot-tall monument.
